Description

Overview

Cyanocobalamin is a synthetic, inactive form of vitamin B12 that must be converted into methylcobalamin or adenosylcobalamin before the body can use it. It is widely used in vitamin supplements and injections for treating B12 deficiency, particularly in people with pernicious anemia, malabsorption disorders, or dietary insufficiencies.

Mechanism of Action

Once converted to an active form, cyanocobalamin aids in red blood cell production, neurological function, and DNA synthesis. It plays a key role in methylation reactions, which regulate gene expression, detoxification, and neurotransmitter function. It also helps in the conversion of homocysteine to methionine, promoting cardiovascular health.

Benefits and Indications

• Prevention and Treatment of B12 Deficiency: Essential for individuals with vegan diets, gastrointestinal disorders, or pernicious anemia.
• Supports Neurological Health: Helps prevent nerve damage and neuropathy.
• Enhances Energy Production: Reduces fatigue by supporting ATP synthesis.
• Promotes Healthy Skin and Hair: Vital for cellular regeneration.

Possible Side Effects

• Mild gastrointestinal upset
• Dizziness or headache
• Rare allergic reactions

Drug Interactions

• Alcohol: Reduces absorption.
• Aminoglycoside Antibiotics (e.g., gentamicin): May decrease B12 levels.