Description

Description: A muscle relaxant used to treat spasticity associated with multiple sclerosis and spinal cord injuries.

Indication: Indicated for muscle spasticity in conditions such as multiple sclerosis and cerebral palsy.

Contraindications: Contraindicated in patients with hypersensitivity to baclofen and those with severe renal impairment.

Mechanism of Action: Acts on GABA-B receptors in the spinal cord, reducing nerve signal transmission and muscle spasticity.

Side Effects: Common side effects include drowsiness, dizziness, weakness, and fatigue. Withdrawal can cause seizures and hallucinations.

Drug Interactions: Enhances effects of CNS depressants such as opioids and benzodiazepines, increasing sedation risk.