Description

Overview

Bi-Est is a compounded bioidentical hormone formulation containing 80% estriol and 20% estradiol, used for hormone replacement therapy (HRT).

Mechanism of Action

Estriol and estradiol bind to estrogen receptors, regulating gene expression related to reproductive and metabolic health.

Benefits and Indications

• Menopausal symptom relief
• Vaginal atrophy treatment
• Bone health support

Possible Side Effects

• Breast tenderness
• Increased clotting risk
• Mood changes

Drug Interactions

• CYP3A4 inhibitors (can increase estrogen levels)