Description

Overview
Meloxicam is a prescription NSAID primarily used for pain and inflammation associated with arthritis. Unlike ibuprofen or naproxen, meloxicam is a selective COX-2 inhibitor, meaning it has a lower risk of causing stomach ulcers while still providing effective pain relief.

Mechanism of Action
Meloxicam inhibits cyclooxygenase-2 (COX-2) enzyme more selectively than traditional NSAIDs, reducing prostaglandin production responsible for pain and inflammation. While it still has some COX-1 inhibition, it is generally gentler on the stomach than ibuprofen or naproxen.

Benefits and Indications
• Osteoarthritis – Effective for reducing joint pain and stiffness.
• Rheumatoid arthritis – Helps control chronic inflammation in autoimmune arthritis.
• Ankylosing spondylitis – Used for inflammatory spinal conditions.
• General musculoskeletal pain – Can be prescribed for strains, sprains, and injuries.

Possible Side Effects
• Gastrointestinal effects – Though less than traditional NSAIDs, ulcers, nausea, and stomach pain can still occur.
• Heart risks – Long-term use may increase cardiovascular risks like heart attack or stroke.
• Kidney damage – Can reduce kidney function, especially in older adults.
• Liver concerns – Rare cases of liver toxicity reported.