Description
Overview
Mirtazapine is an atypical antidepressant known for its sedative and appetite-stimulating effects. It is often prescribed for depression with insomnia or weight loss.
Mechanism of Action
Mirtazapine blocks alpha-2 adrenergic receptors, leading to increased serotonin and norepinephrine levels. It also acts on histamine receptors, making it a powerful sedative.
Benefits and Indications
• Major depressive disorder (MDD) – Especially for people with sleep disturbances.
• Anxiety disorders – Helps with generalized anxiety disorder (GAD) and panic disorder.
• Insomnia and poor appetite – Often used for patients who struggle with eating and sleeping.
Possible Side Effects
• Weight gain and increased appetite – Can be beneficial or undesirable.
• Drowsiness – Strong sedative effect.
• Dizziness and dry mouth – Common mild side effects.
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